(3aR,6aS)-5-(1H-吲哚-5-羰基)六氫吡咯并[3,4-c]吡咯-2 (IH)-甲酸3, 5-二氯 節(jié)酯; (3aR,6aS)-5-(9H-咔唑-3-羰基)六氫吡咯并[3,4-c]吡咯-2 (IH)-甲酸3, 5-二氯 節(jié)酯; (3&1?,6&5)-5-(1!1-吲唑-5-羰基)六氫吡咯并[3,4-(3]吡咯-2(1!1)-甲酸3,5-二氯 節(jié)酯; (3&1?,6&5)-5-(1!1-苯并[(1]咪唑-5-羰基)六氫吡咯并[3,4-(3]吡咯-2(1!1)-甲酸 3, 5-二氯芐酯; 反式-2-(1H-苯并[d] [1,2, 3]三唑-5-羰基)六氫-IH-吡咯并[3,4-c]吡 啶-5 (6H)-甲酸3, 5-二氯芐酯; 順式-2-(1H-苯并[d] [1,2, 3]三唑-5-羰基)六氫-IH-吡咯并[3,4-c]吡 啶-5 (6H)-甲酸3, 5-二氯芐酯; (3aR,8aS)-2-(lH-苯并[d][l,2,3]三唑-5-羰基)八氫吡咯并[3,4-d]氮雜章 -6 (7H)-甲酸3, 5-二氯芐酯; (1H-苯并三唑-5-基)-{(3aS,6aR) -5- [2- (3-氯-苯基)-乙磺?;鵠-六氫-吡咯并 [3,4-c]吡咯-2-基}-甲酮; (3aR,6aS)-5-(4,5,6,7-四氫-IH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3, 4-c]吡咯-2 (IH)-甲酸3, 5-二氯芐酯; 1-((3&1?,8&5)-2-(1!1-苯并[(1][1,2,3]三唑-5-羰基)八氫吡咯并[3,4-(1]氮雜章. -6 (7H)-基)-3- (3-氯苯基)-2, 2-二甲基丙-1-酮; 出)-1-((3&1?,8&5)-2-(1!1-苯并[(1][1,2,3]三唑-5-羰基)八氫吡咯并[3,4-(1]氮雜 草.-6 (7H)-基)-3-(3-氟-4-(三氟甲氧基)苯基)丙-2-烯-1-酮; (3aSR,6SR,7aSR) -6- {(3aS,8aR) -6- [ (E) -3- (4-三氟甲氧基-苯基)-丙烯酰基]-八 氫-吡咯并[3,4-d]氮雜草.-2-羰基}-六氫-苯并噁唑-2-酮; 伍)-1-[(3&5,8&1〇-2-(苯并[(3][1,2,5]噁二唑-5-羰基)-八氫-吡咯并[3,4-(1]氮 雜萆.-6-基]-3- (4-三氟甲氧基-苯基)-丙-2-烯-1-酮; 出)-1-((3&1?,8&5)-2-(1!1-苯并[(1][1,2,3]三唑-5-羰基)八氫吡咯并[3,4-(1]氮雜 草,-6(7H)_基)-3-(2-甲基-4-(三氟甲氧基)苯基)丙-2-烯-1-酮; 出)-1-((3&1?,8&5)-2-(1!1-苯并[(1][1,2,3]三唑-5-羰基)八氫吡咯并[3,4-(1]氮雜 簞I -6 (7H)-基)-3- (3-氟-4-甲氧基苯基)丙-2-烯-1-酮; (E) -1-[ (3aS,8aR) -2- ((S) -4, 5,6, 7-四氫-IH-苯并三唑-5-羰基)-八氫-吡咯并 [3,4-d]氮雜草1 -6-基]-3- (4-三氟甲氧基-苯基)-丙-2-烯-1-酮 (E) -I-[ (3aS,8aR) -2- ((R) -4, 5,6, 7-四氫-IH-苯并三唑-5-羰基)-八氫-吡咯并 [3,4-d]氮雜罩_ -6-基]-3- (4-三氟甲氧基-苯基)-丙-2-烯-1-酮 (E) -I- [ (3aS,8aR) -2- (1H-苯并三唑-5-羰基)-八氫-吡咯并[3,4-d]氮雜簞, -6-基]-3-(2-異丙基-苯基)-丙-2-烯-1-酮; 反式-2_ (2-氧代-2, 3-二氫苯并[d]卩惡唑_6_撰基)六氫-IH-批咯并[3,4_c]批 啶-5 (6H)-甲酸3, 5-二氯芐酯; (3aR,6aS)-5-(2-氧代-2,3-二氫苯并[d]囉唑-6-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸3, 5-二氯芐酯; 6- {(3aS,8aR) -6- [ (E) -3- (4-三氟甲氧基-苯基)-丙烯?;鵠-八氫-吡咯并[3,4-d] 氮雜罩_ -2-羰基} -3H-苯并卩惡唑-2-酮; (3&尺,58,635)-5-(2-氧代-2,3-二氫1苯并[(1]卩惡唑-6-基氧基)六氫1環(huán)戊二稀并[(3] 吡咯-2 (IH)-甲酸3, 5-二氯芐酯; (3&1?,51',633)-5-(2-氧代-2,3-二氫1苯并[(1]卩惡唑-6-基氧基)六氫 1環(huán)戊二稀并[(3] 吡咯-2 (IH)-甲酸3, 5-二氯芐酯; (3aS,6aS)-5-(lH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸3, 5-二氯芐酯; 反式-5-(1Η-苯并三唑-5-羰基)-八氫-吡咯并[3,4-c]吡啶-2-甲酸3-甲磺酰 基-5-三氟甲基-芐酯; (3aR,6aR)-5-(lH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸3, 5-二氯芐酯; (3aS,6aS)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 3-氯-5-甲磺?;?芐酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 3-氯-5-甲磺?;?芐酯; (3aS,8aR) -2- (1H-苯并三唑-5-羰基)-八氫-吡咯并[3,4-d]氮雜草-6-甲酸3-甲 磺?;?5-三氟甲基-芐酯; (3aS,8aR)-2-(lH-苯并三唑-5-羰基)-八氫-吡咯并[3,4-d]氮雜草-6-甲酸 3-氯-5-甲磺?;?芐酯; (3aS,6aR)-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸3-甲磺 ?;?5-三氟甲基-芐酯; 順式-5-(1H-苯并[d] [1,2, 3]三唑-5-羰基)六氫-IH-吡咯并[3,4-c]吡 啶-2 (3H)-甲酸3, 5-二氯芐酯; (3aS,7aR)-5-(lH-苯并三唑-5-羰基)-八氫-吡咯并[3,4-c]吡啶-2-甲酸 3-氯-5-甲磺?;?芐酯; 反式-5-(1H-苯并[d] [1,2, 3]三唑-5-羰基)六氫-IH-吡咯并[3,4-c]吡 啶-2 (3H)-甲酸3, 5-二氯芐酯; (3aR,8aS)-6-(lH-苯并[d][l,2,3]三唑-5-羰基)八氫吡咯并[3,4-d]氮雜章 -2 (IH)-甲酸3, 5-二氯芐酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 1-(3-氯-苯基)_環(huán)丙酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸二環(huán) [4. 1.0]庚-7-基甲酯; (3&5,6&1〇-5-(1!1-苯并三唑-5-羰基)-六氫-吡咯并[3,4-(3]吡咯-2-甲酸金剛 燒-2-基甲酯; (3aS,6aR) -5- (1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]批咯-2-甲酸1-氟-環(huán) 己基甲酯; (3aS,6aR)-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸2-金剛 燒-2-基-乙酯; (3aS,6aR)-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸2-金剛 燒-1-基-乙酯; (3&5,6&1〇-5-(1!1-苯并三唑-5-羰基)-六氫-吡咯并[3,4-(3]吡咯-2-甲酸金剛 燒-1-基甲酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸環(huán)己基 甲酯; 順式-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸3-(2, 2, 2-三 氟-1-甲氧基-乙基)-芐酯; 順式-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸3-(2, 2, 2-三 氟_1-羥基-乙基)-節(jié)酯; (3aR,6aS)-5-(lH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸2-環(huán)己基乙酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 3-氟-5_二氟甲氧基-節(jié)酯; (3aR,6aS)-5-(lH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸3-氯-5-氰基芐酯; (3aS,6aR)-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸3-三氟 甲氧基-芐酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 3-氟-5-二氟甲基-節(jié)酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 3- 氯-5_二氟甲氧基-節(jié)酯; (3aS,6aR)-5-(lH-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸 4- 氟-3_二氟甲氧基-節(jié)酯; (3aR,6aS)-5-(lH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸3-氰基-5-氟芐酯; (3aR,6aS)-5-(lH-苯并[d] [1,2,3]三唑-5-羰基)六氫吡咯并[3,4-c]吡 咯-2 (IH)-甲酸3-氯-5-甲氧基芐酯; (3&5,6&1〇-5-(1!1-苯并三唑-5-羰基)-六氫-吡咯并[3,4-(3]吡咯-2-甲酸(15, 4R)-3-甲基-二環(huán)[2. 2. 1]庚-2-基甲酯; (3&5,6&1〇-5-(1!1-苯并三唑-5-羰基)-六氫-吡咯并[3,4-(3]吡咯-2-甲酸(11?, 4S)-1-二環(huán)[2·2· 1]庚-2-基甲酯; (3aR,5S,6aS)-5-[(3H-[l,2,3]三唑-4-基甲基)-氨基甲酰基]-六氫-環(huán)戊二烯并 [c]吡咯-2-甲酸3, 5-二氯-芐酯; (3aS,6aS)-5-(l,4,6,7-四氫-[1,2,3]三唑并[4,5-c]吡啶-5-羰基)-六氫-吡咯 并[3,4-c]吡咯-2-甲酸3-氯-5-甲磺?;?芐酯; (3aS,6aR)-5-[(lH-[l,2,3]三唑-4-基甲基)-氨基甲酰基]-六氫-吡咯并[3,4-c] 吡咯-2-甲酸3, 5-二氯-芐酯; (3aS,6aS)-5-(1H-苯并三唑-5-羰基)-六氫-吡咯并[3,4-c]吡咯-2-甲酸4-三氟 甲氧基-芐酯; (3&1?,51',6&3)-5-(2-氧代-2,3-二氫苯并[(1]1猓唑-6-基氨基)六氫環(huán)戊二烯并[(3] 吡咯-2 (IH)-甲酸3, 5-二氯芐酯; (3&1?,6&5)-5-((1!1-苯并[(1]咪唑-5-基)甲基)六氫吡咯并[3,4-(3]吡咯-2(1!1)-甲 酸3, 5-二氯芐酯; 1-((3&1?,6&5)-5-((1!1-苯并[(1][1,2,3]三唑-5-基)甲基)六氫吡咯并[3,4-(3]吡 咯-2 (IH)-基)-3-(3,5_ 二氯苯基)丙-1-酮; (3aR,6aS)-5-((lH-吲唑-5-基)甲基)六氫吡咯并[3,4-c]吡咯-2(1H)-甲酸3, 5_二氯芐酯; (3&1?,6&5)-5-((2-氧代-2,3-二氫苯并[(1]丨1惡唑-6-基)甲基)六氫吡咯并[3,4-(3] 吡咯-2 (IH)-甲酸3, 5-二氯芐酯; 6-(((3aR,6aS)-5-(3-(3,5-二氯苯基)丙?;┝鶜溥量┎3,4-c]吡 咯-2 (IH)-基)甲基)苯并[d] _唑-2 (3H)-酮; 4-{^)-3-[(3&5,8&1〇-2-(1!1-苯并三唑-5-基甲基)-八氫-吡咯并[3,4-(1]氮雜罩. -6-基]-3-氧代-丙烯基}-苯甲腈; (E)-1-[(3aS,8aR)-2-(lH-苯并三唑-5-基甲基)-八氫-吡咯并[3,4-d]氮雜罩 -6-基]-3- (4-三氟甲氧基-苯基)-丙-2-烯-1-酮; (3&1?,6&3)-5-(2-氧代-2,3-二氫苯并[(1]卩惡唑-6-基磺?;┝鶜溥量┎3,4-(3] 吡咯-2 (IH)-甲酸3, 5-二氯芐酯; (3aR,6aS)-5-(4,5,6,7-四氫-1H-[1,2,3]三唑并[4,5-c]吡啶-5-羰基)六氫吡咯 并[3,4-c]吡咯-2 (IH)-甲酸3, 5-二氯芐酯; (E)-1-[(3aS,8aR)-2-(l,4,6,7-四氫-[1,2,3]三唑并[4,5-c]吡啶-5-羰基)-八 氫-吡咯并[3,4-d]氮雜草.-6-基]-3-(4-三氟甲氧基-苯基)-丙-2-烯-1-酮; (E) -I- [ (3aS,8aR) -2- (1,4,6, 7-四氫-吡唑并[4, 3-c]吡啶-5-羰基)-八氫-吡咯 并[3,4-d]氮雜草1 -6-基]-3- (4-三氟甲氧基-苯基)-丙-2-烯-1-酮; 順式_5_((3&1?,833)-6-(出)-3-(4-(二氟甲氧基)苯基)丙烯?;┦畾渑┎3, 4-(1]氮雜草-2-羰基)六氫卩惡唑并[5,4-(3]吡啶-2(1!1)-酮; 6- {(3aS,8aR) -6- [ (E) -3- (4-三氟甲氧基-苯基)-丙烯?;鵠-八氫-吡咯并[3,4-d] 氮雜萆-2-羰基} _5,6, 7,8-四氫-1H-[1,6]萘啶-2-酮; (3aR,7aR) _5_ {(3aS,8aR) _6_[ (E) _3_ (4_ 二氣甲氧基-苯基)-丙稀醜基]-八氧-批 咯并[3,4-d]氮雜草-2-羰基}-六氫-噁唑并[5,4-c]吡啶-2-酮; (E) -1-[ (3aS,8aR) -2- (7,8-二氫-5H-[1,6]萘啶-6-羰基)-八氫-吡咯并[3,4-d] 氮雜草.-6-基]-3- (4-三氟甲氧基-苯基)-丙-2-烯-1-酮; (E)-3_(4_ 二氣甲氧基-苯基)-1-[(3aS,8aR)-2_(2-二氣甲基 _5,6_ 二 氫-8H-[1,2,4]三唑并[l,5-a]吡嗪-7-羰基)-八氫-吡咯并[3,4-d]氮雜萆 -6-基]-丙-2-烯-1-酮; (3&3,8&1?)-6-[出)