組織病理切片，H&E染色，油紅染色，以測定 脂肪肝的程度。
[0200] (f)試驗終點（4-6個月喂養(yǎng)）后回腸區(qū)段組織染色，PAS染色，以確定腸道界面， 包括腸道表面粘多糖（mucine)的完整成度。通過測定回腸DEFA5以及MMP7染色，以確定 腸道防御素的程度。
[0201] (g)測定血液中25-OH維生素03的含量。
[0202] (h)在試驗中我們也應(yīng)用了一種alpha防御素的突變體，其一級結(jié)構(gòu)為mut_Defa5 :ATSYARTGESATAESLSGVAEISGSLYSLSAE。
[0203] 最后需要說明的是，以上實施例僅用于幫助本領(lǐng)域技術(shù)人員理解本發(fā)明的實質(zhì)， 并不用作本發(fā)明保護范圍的限定。
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