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雙調(diào)蛋白特異性-雙螺旋寡核糖核苷酸,包含雙螺旋寡核糖核苷酸的雙螺旋寡核糖核苷酸...的制作方法_3

文檔序號:8460345閱讀:來源:國知局
' (SEQ ID NO:103),
[0145] 5' -cugcuggauuggaccucaa-3' (SEQ ID NO:104),
[0146] 5' -ugauucagucagaguugaa-3' (SEQ ID NO:105),
[0147] 5' -ucgacaagagaauggaaau-3' (SEQ ID NO:106),
[0148] 5' -cucaagaagugagaugucu-3' (SEQ ID NO:107),
[0149] 5' -uucugcauucacggagaau-3' (SEQ ID NO:108),
[0150] 5' -agguuaccucaagaaguga-3' (SEQ ID NO:109),
[0151] 5' -aaugccuucuaguagugaa-3' (SEQ ID NO:110),
[0152] 5' -augauucagucagaguuga-3' (SEQ ID NO:111),
[0153] 5' -aaacaagacggaaagugaa-3' (SEQ ID NO:112),
[0154] 5' -uuucugcauucacggagaa-3' (SEQ ID NO:113),
[0155] 5' -caaauaccuggcuauauug-3' (SEQ ID NO:114),
[0156] 5' -gaagcaguaacaugcaaau-3' (SEQ ID NO:115),
[0157] 5' -gacuacucagaagaguaug-3' (SEQ ID NO:116),
[0158] 5' -gaugauucagucagaguug-3' (SEQ ID NO:117),
[0159] 5' -ugcauucacggagaaugca-3' (SEQ ID NO:118),
[0160] 5' -gcugaggaacgaaagaaac-3' (SEQ ID NO:119),
[0161]5' -uggauuugagguuaccuca-3' (SEQ ID NO:120),
[0162]5' -agugagaugucuucaggga-3' (SEQ ID NO:121),
[0163]5' -gagguuaccucaagaagug-3' (SEQ ID NO:122),
[0164] 5' -cuucgacaagagaauggaa-3' (SEQ ID NO:123),
[0165]5' -cucuugauacucggcucag-3' (SEQ ID NO:124),
[0166]5' -gucagaguugaacagguag-3' (SEQ ID NO:125),
[0167] 5' -caugaaaacucacagcaug-3' (SEQ ID NO:126),
[0168]5' -ggaaauguacaugcuauag-3' (SEQ ID NO:127),
[0169] 5' -cauguaaugcagaauuuca-3' (SEQ ID NO:128),
[0170]5' -gauugacaguaguuuauca-3' (SEQ ID NO:129),
[0171]5' -guccagcuuagaagacaau-3' (SEQ ID NO:130),
[0172]5' -ugcuggauuggaccucaau-3' (SEQ ID NO:131),
[0173] 5' -gaagacaauacgucaggaa-3' (SEQ ID NO:132),
[0174] 5' -aagacaauacgucaggaaa-3' (SEQ ID NO:133),
[0175]5' -ugaggaacgaaagaaacuu-3' (SEQ ID NO:134),
[0176] 5' -uucgacaagagaauggaaa-3' (SEQ ID NO:135),
[0177]5' -ugcuguuauuacaguccag-3' (SEQ ID NO:136),
[0178]5' -gauggauuugagguuaccu-3' (SEQ ID NO:137),
[0179] 5' -cucaaugacaccuacucug-3' (SEQ ID NO:138),
[0180] 5' -gguuaccucaagaagugag-3' (SEQ ID NO:139),
[0181] 5' -gccgacuaugacuacucag-3' (SEQ ID NO:140),
[0182] 5' -caaauauauagagcaccug-3' (SEQ ID NO:141),
[0183] 5' -agccgacuaugacuacuca-3' (SEQ ID NO:142),
[0184] 5' -accuggcuauauugucgau-3' (SEQ ID NO:143),
[0185] 5' -ccuacucugggaagcguga-3' (SEQ ID NO:144),
[0186] 5' -gcauuagcagccauagcug-3' (SEQ ID NO:145),
[0187] 5' -augauaacgaaccacaaau-3' (SEQ ID NO:146),
[0188] 5' -gcgugaaccauuuucuggg-3' (SEQ ID NO:147),
[0189] 5' -ugggaagcgugaaccauuu-3' (SEQ ID NO:148),
[0190] 5' -agcaguaacaugcaaaugu-3' (SEQ ID NO:149),
[0191] 5' -ugaaaacucacagcaugau-3' (SEQ ID NO:150),
[0192] 5' -agacaauacgucaggaaau-3' (SEQ ID NO:151),
[0193] 5' -auacucggcucaggccauu-3' (SEQ ID NO:152),
[0194] 5' -auuaugcugcuggauugga-3' (SEQ ID NO:153),
[0195] 5' -ugcugauggauuugagguu-3' (SEQ ID NO:154),
[0196] 5' -ugugagugaaaugccuucu-3' (SEQ ID NO:155),
[0197] 5' -auucagucagaguugaaca-3' (SEQ ID NO:156),
[0198] 5' -aagggaggcaaaaauggaa-3' (SEQ ID NO:157),
[0199] 5' -uguuauuacaguccagcuu-3' (SEQ ID NO:158),
[0200]5' -acgaaagaaacuucgacaa-3' (SEQ ID NO:159),
[0201] 5' -cugcauucacggagaaugc-3' (SEQ ID NO:160),
[0202] 5' -agagaauggaaauguacau-3' (SEQ ID NO:161),
[0203]5' -cgucaggaaauaugaagga-3' (SEQ ID NO:162),
[0204]5' -augcugcuggauuggaccu-3' (SEQ ID NO:163),
[0205]5' -aguaugauaacgaaccaca-3' (SEQ ID NO:164),
[0206] 5' -aaccacaaauaccuggcua-3' (SEQ ID NO:165),
[0207]5' -aauauauagagcaccugga-3' (SEQ ID NO:166),
[0208] 5' -aaauugcauuagcagccau-3' (SEQ ID NO:167),
[0209]5' -acgaaccacaaauaccugg-3' (SEQ ID NO:168),
[0210]5' -aagcaguaacaugcaaaug-3' (SEQ ID NO:169),
[0211] 5' -cgcucuugauacucggcuc-3' (SEQ ID NO:170),
[0212] 5' -guaacaugcaaaugucagc-3' (SEQ ID NO:171),
[0213]5' -aauguacaugcuauagcau-3' (SEQ ID NO:172),
[0214]5' -cacggagaaugcaaauaua-3' (SEQ ID NO:173),
[0215]5' -cuguuauuacaguccagcu-3' (SEQ ID NO:174),
[0216]5' -cgacaagagaauggaaaug-3' (SEQ ID NO:175),
[0217]5' -aaaacaagacggaaaguga-3' (SEQ ID NO:176),
[0218] 5' -cuauauugucgaugauuca-3' (SEQ ID NO:177),
[0219] 5' -aguccaugaaaacucacag-3' (SEQ ID NO:178),
[0220] 5' -gcugucgcucuugauacuc-3' (SEQ ID NO:179),
[0221] 5' -gcuauauugucgaugauuc-3' (SEQ ID NO:180),
[0222] 5' -cgaaagaaacuucgacaag-3' (SEQ ID NO:181),
[0223] 5' -agcgugaaccauuuucugg-3' (SEQ ID NO:182),
[0224] 5' -augaaaacucacagcauga-3' (SEQ ID NO:183),
[0225] 5' -acuucgacaagagaaugga-3' (SEQ ID NO:184),
[0226] 5' -caguccagcuuagaagaca-3' (SEQ ID NO:185),
[0227] 5' -ugcaaauauauagagcacc-3' (SEQ ID NO:186),
[0228] 5' -agaagacaauacgucagga-3' (SEQ ID NO:187),
[0229] 5' -gggagccgacuaugacuac-3' (SEQ ID NO:188),
[0230] 5' -auggaaauguacaugcuau-3' (SEQ ID NO:189),
[0231] 5' -caaaaauugcauuagcagc-3' (SEQ ID NO:190),
[0232] 5' -gugcugucgcucuugauac-3' (SEQ ID NO:191),
[0233] 5' -ugcugucgcucuugauacu-3' (SEQ ID NO:192),
[0234] 5' -uacucggcucaggccauua-3' (SEQ ID NO:193),
[0235] 5' -uggcuauauugucgaugau-3' (SEQ ID NO:194),
[0236] 5' -auucacggagaaugcaaau-3' (SEQ ID NO:195),
[0237] 5' -aaacucacagcaugauuga-3' (SEQ ID NO:196),
[0238] 5' -auuacaguccagcuuagaa-3' (SEQ ID NO:197),
[0239] 5' -ugauggauuugagguuacc-3' (SEQIDNO:198),
[0240] 5' -ucagaagaguaugauaacg-3' (SEQIDNO:199),
[0241] 5' -agaguaugauaacgaacca-3' (SEQIDN0:200),
[0242] 5' -ugauaacgaaccacaaaua-3' (SEQIDN0:201),
[0243] 5' -acggagaaugcaaauauau-3' (SEQIDN0:202),
[0244] 5' -cuaguagugaaccguccuc-3' (SEQIDN0:203),
[0245] 5' -gaagaguaugauaacgaac-3' (SEQIDN0:204),
[0246] 5' -aaaugccuucuaguaguga-3' (SEQIDN0:205),
[0247] 51 -uaacgaaccacaaauaccu-3/(SEQIDNO:206),
[0248] 5' -auugucgaugauucaguca-3' (SEQIDN0:207),
[0249] 5f -acaugcaaaugucagcaag-3r(SEQIDNO:208),
[0250] 5f -uguugcuguuauuacaguc-3r(SEQIDNO:209),
[0251] 5f -uagagcaccuggaagcagu-3/(SEQIDNO:210),
[0252] 5' -aacgaaagaaacuucgaca-3' (SEQIDNO:211),
[0253] 5' -aaauaccuggcuauauugu-3' (SEQIDN0:212),
[0254] 5' -aauacgucaggaaauauga-3' (SEQIDN0:213),
[0255] 5' -uggaaauguacaugcuaua-3' (SEQIDN0:214),
[0256] 5f -acgucaggaaauaugaagg-3/(SEQIDNO:215),
[0257] 5' -uuggaccucaaugacaccu-3' (SEQIDN0:216),
[0258] 5' -uaacaugcaaaugucagca-3' (SEQIDN0:217),
[0259] 5' -augacuacucagaagagua-3' (SEQIDN0:218),
[0260] 5' -aaauccauguaaugcagaa-3' (SEQIDN0:219),
[0261] 5' -ggaagcgugaaccauuuuc-3' (SEQIDN0:220),
[0262] 5' -ucugggaagcgugaaccau-3' (SEQIDN0:221),
[0263] 5' -uauugucgaugauucaguc-3' (SEQIDN0:222),
[0264] 5' -aguaacaugcaaaugucag-3' (SEQIDN0:223),
[0265] 5' -uuagaagacaauacgucag-3' (SEQIDN0:224),
[0266] 51 -aaaauccauguaaugcaga-3/(SEQIDNO:225),
[0267] 5' -gcug
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